ea0034p42 | Clinical biochemistry | SFEBES2014
Neophytou Christina
, Darch Sarah
, Gill Jasdeep Singh
, Hancock Maggie
, Meeran Karim
, Palazzo Fausto
, Tan Tricia
Phaeochromocytomas (PCC) and paragangliomas (PGL) are rare tumours derived from the sympathetic or parasympathetic paraganglia. They characteristically secrete catecholamines (noradrenaline/adrenaline/dopamine), which are metabolised to the metanephrines (normetadrenaline/metadrenaline/3-MT respectively). These tumour markers can be detected in acidified 24-h urine collections as first-line investigative tests. Plasma 3-MT has been characterised as a biomarker of metastatic PG...